g(s*) within -∞ < s* < ∞

The apparent sedimentation coefficient, s*, and its distribution function, g(s*), within -∞ < s* < ∞.

Link to the latest draft: g(s*) draft of July 31, 2015. (First published on May 9, 2012.)

This document applies material from An irreversible thermodynamic description of analytical ultracentrifugation (AUC) applied to a solution of the time- and gravitational-potential-space-dependent Lamm equation, and An irreversible thermodynamic description of membrane-confined electrophoresis (MCE) applied to a solution of the time- and electrical-potential-space-dependent continuity equation for MCE, to which links are provided in an accompanying post (Irreversible thermodynamics of AUC and MCE).

This document also includes analyses of selected data sets from Johnston-Ogston effects in AUC simulations of two model systems based on polystyrene beads that are polydisperse with respect to specific gravity, to which a link is provided in an accompanying post (Johnston-Ogston effects with PS beads). Additionally, this document describes the method of analysis used in Distinguishing hypothetical systems of PS beads by g(s*) analysis of simulated AUC data to which noise has been added, and quantifying the statistical significance of any observed distinguishability (Effects of noise on the distinguishability of several simulated AUC systems of PS beads) to obtain observations for each replicate within each treatment group at selected times.

Leave a comment